Allogeneic stem cells

Stem cells that are used clinically to augment, repair, replace or regenerate organs and tissues and are derived from a cell source that is genetically different from the host/recipient.

A hematopoietic stem cell transplant (bone marrow transplant) is an example of a clinical allogeneic transplant in which the patient receives blood-forming hematopoietic stem cells from a genetically similar, but not identical, donor. Allogeneic hematopoietic stem cells are derived from donated bone marrow or umbilical cord blood.

An autologous stem cell transplant uses the patient's own cells to augment, repair, replace or regenerate diseased and/or damaged organs and tissues. There are currently no autologous stem cell therapies in clinical use.