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SlideshowReport

The life cycle of HIV

Description
An HIV virion (1) invades a host cell by binding to two proteins on the cell's surface (2), allowing the virion to spill its contents into the cell (3). Once inside the host cell, HIV's reverse transcriptase makes a DNA copy of the viral genome (4). HIV's integrase inserts this DNA copy into the host cell's genome (5).The host cell's RNA polymerase transcribes the viral genome into messenger RNA (6), and the host cell's ribosomes transcribe the viral mRNA into precursor proteins (7). HIV's protease cleaves the precursors, yielding mature viral proteins (8). New virions assemble in the host cell's cytoplasm (9), then bud from the host cell's membrane (10).
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