Top Posters
Since Sunday
5
o
5
4
m
4
b
4
x
4
a
4
l
4
t
4
S
4
m
3
s
3
SlideshowReport

A missense mutation that causes red blood cells to sickle in sickle-cell anemia.

Tags
Description
Scanning electron micrographs of (a) normal red blood cells and (b) sickled red blood cells. As shown above the micrographs, a missense mutation in the ?-globin gene (which codes for a subunit of hemoglobin) changes the sixth amino acid in the ?-globin polypeptide from a glutamic acid to a valine. (c) This micrograph shows how this alteration to the structure of ?-globin causes the formation of abnormal fibrelike structures. In normal cells, hemoglobin proteins do not form fibres.
Related Images
Add Comment
Explore
Post your homework questions and get free online help from our incredible volunteers
  969 People Browsing
Your Opinion
Which industry do you think artificial intelligence (AI) will impact the most?
Votes: 308