Title: PhysioEx 8.0 exercise 4 endocrine system physiology Post by: bay1 on Jan 25, 2011 I cannot figure out activity 1 # 12, activity 4 # 7 activity 8 # 17
Title: Re: PhysioEx 8.0 exercise 4 endocrine system physiology Post by: duddy on Jan 25, 2011 I cannot figure out activity 1 # 12, activity 4 # 7 activity 8 # 17
Don't have 1. #12 Activity 4: Determining the Effect of Propylthiouracil on Metabolic Rate (p. 48) 7. On the normal rat, the metabolic rate after propylthiouracil injection is slower than the baseline metabolic rate. Propylthiouracil is antagonistic to thyroxine and will tend to decrease the effects of thyroxine. On the thyroidectomized rat, the metabolic rate after propylthiouracil injection is the same as the baseline metabolic rate. Since the thyroidectomized rat cannot make any thyroxine, the propylthiouracil has nothing to be antagonistic to and therefore has no effect. On the hypophysectomized rat, the metabolic rate after propylthiouracil injection is the same as the baseline metabolic rate. Since the hypophysectomized rat does not have a functional thyroid gland, no thyroxine is being made and there is nothing for the propylthiouracil to be antagonistic to. Activity 8: Measuring Cortisol and Adrenocorticotropic Hormone (pp. 55–57) 17. Patient 1: cortisol 3 ± 1 mcg/dL Low ACTH 18 ± 2 pg/ml Low Patient 2: cortisol 35 ± 5 mcg/dL High ACTH 13 ± 2 pg/ml Low Patient 3: cortisol 45 ± 5 mcg/dL High ACTH 86 ± 5 pg/ml High Patient 4: cortisol 3 ± 1 mcg/dL Low ACTH 100 ± 5 pg/ml High Patient 5: cortisol 50 ± 5 mcg/dL High ACTH 18 ± 2 pg/ml Low If you want further assistance, you have to have >25 posts Title: Re: PhysioEx 8.0 exercise 4 endocrine system physiology Post by: boeing on Jan 31, 2011 This is probably a bit late but Activity 1 #12 is not given in duddy's answer key because you have to use data that you have collected and recorded in chart 1. After you convert the weight data from grams to kilograms use the formula given to determine the metabolic rate. These answers will vary depending on what you have on your chart.
Title: Re: PhysioEx 8.0 exercise 4 endocrine system physiology Post by: gee.amanda on Feb 26, 2011 Activity 1 #12
Your answers go written on the chart BASELINE normal rat: 1741.1 ml O2/kg./Hr Thyroidectomized Rat: 1496.9 ml O2/Kg./Hr Hypophysectomized Rat: 1489.0 ml O2/Kg./Hr Answers may vary though. Those are just some of mine Title: Re: PhysioEx 8.0 exercise 4 endocrine system physiology Post by: halleypep on Mar 1, 2011 Activity 1 #12 - 1678.7 ml O2/kg/hr
Title: Re: PhysioEx 8.0 exercise 4 endocrine system physiology Post by: biosux on Mar 1, 2011 normal rat: 1741.1 ml O2/kg./Hr
Thyroidectomized Rat: 1496.9 ml O2/Kg./Hr Hypophysectomized Rat: 1489.0 ml O2/Kg./Hr Title: Re: PhysioEx 8.0 exercise 4 endocrine system physiology Post by: kkarg78 on Jul 23, 2011 Activity 8: Measuring Cortisol and Adrenocorticotropic Hormone - This is broke down for you but it is all of Question 17.
1. Patient 1: Cortisol: 2.86 mcg/dL 2. High or Low? low 3. Patient 1: ACTH: 18.40 pg/ml 4. High or Low? low 5. Patient 2: Cortisol: 32.25 mcg/dL 6. High or Low? high 7. Patient : ACTH: 11.72 pg/ml 8. High or Low? low 9. Patient 3: Cortisol: 41.94 mcg/dL 10. High or Low? high 11. Patient 3: ACTH: 90.43 pg/ml 12. High or Low? high 13. Patient 4: Cortisol: 3.99 mcg/dL 14. High or Low? low 15. Patient 4: ACTH: 95.38 pg/ml 16. High or Low? high 17. Patient 5: Cortisol: 52.93 mcg/dL 18. High or Low? high 19. Patient 5: ACTH: 18.37 pg/ml 20. High or Low? low Title: Re: PhysioEx 8.0 exercise 4 endocrine system physiology Post by: kkarg78 on Jul 23, 2011 Exercise 4: Activity 4: Determining the Effect of Propylthiouracil on Metabolic Rate
1. What was the effect of propylthiouracil on the normal rat’s metabolic rate? It caused the rate to decrease. How does it compare to the normal rat’s baseline metabolic rate? The metabolic rate of the baseline rat was significantly higher 2. Why was this effect seen? Injected with tyroxine caused an increase in grams and ml of O2 levels, because the tyroxine is a hormone from tyroid gland which increase the basal metabolic rate. 3. What was the effect of propylthiouracil on the thyroidectomized rat’s metabolic rate? There was no effect. How does it compare to the thyroidectomized rat’s baseline metabolic rate? The metabolic rate was the same for the two (2) rats. 4. Why was this effect seen? The rat needs both the pituitary glands as well as the thyroid gland to produce thyroxine. PTU inhibits the production of the thyroxine, but thyroxine is already not being produced in this rat due to the absence of the pituitary and/or thyroid glands. 5. What was the effect of propylthiouracil on the hypophysectomized rat’s metabolic rate? There was no effect. How does it compare to the hypophysectomized rat’s baseline metabolic rate? The metabolic rate of the baseline rat was the same for these two (2) rats. 6. Why was this effect seen? Because propylthiouracil is an anti-thyroid drug used to treat hyperthyroidism by decreasing the amount of hormone produced by the thyroid gland and the rat had the thyroid gland removed. |