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eva hornae eva hornae
wrote...
Posts: 36
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9 years ago
The DNA sequence of a portion of gene in the wild-type organism is TTACCATATTCACCC, and the corresponding peptide sequence is Leu-Pro-Tyr_Ser-Pro. The corresponding gene fragment in the phenotypic variant of the organism is TTACCATATTCACCC and the peptide sequence is Leu-Pro-Cys-Ser-Pro. This is an example of a __________ mutation (type) resulting in a ________ mutation (effect).

a). insertion; nonsense
b). basic substitution; missense
c). base substitution; silent
d). deletion; missense
e). base subtitution; nonsense
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wrote...
9 years ago
The two DNA sequences are the same, but there is a change in the Amino acid, so I think you copied the sequence incorrectly.

At any rate, the answer is B.

This is because it has a meaningful change making it a MISSENSE mutation. Since a deletion would cause a frameshift, it must be basic substitution.
eva h. Author
wrote...
9 years ago Edited: 9 years ago, eva hornae
Thank you, adambomber22.  Slight Smile  

I worded the question exactly how it was written on the paper. Smiling Face with Glasses
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