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cr16193 cr16193
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9 years ago
The M and N factors are glycoproteins that are found on the surface of red blood cells. Unlike other types of red blood cell antigens, The M and N factors do not cause antibody reactions in human blood transfusions. People with type M blood are homozygous for the M allele, and people with type N blood are homozygous for the N allele. Heterozygous individuals have type MN blood. In a study of population of Inuit living in the Northwest Territories, 512 people have blood type M, 256 had blood type MN, AND 32 has blood type N.

Now as for my questions...

A) Calculate the frequency of each allele, M and N , in the population studied.

B) WHat would be the expected frequency of each genotype in the next generation, assuming that this population is in genetic equilibrium for the trait.

C) In a second study group, the frequencies of the genotypes were 0.306 MM, 0.491 MN, AND 0.203 NN. Could this second study group have, in fact, come from the previously described Inuit population? Explain your answer...
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wrote...
9 years ago
To solve a) Add the population: 512 + 256 + 32 = 800 people surveyed.

Of those 800, 32 were NN. 32 / 800 is 0.04. 4% of the total population possess this genotype (NN)

On the same note:
   512 / 800 is 0.64. Therefore 64% possess the genotype MM.
   256 / 800 is 0.32. Therefore 32% are heterozygous with the genotype MN.

SQRT(0.04) = 0.2 or 20%. This means that 20% of the population possesses the allele N. 80% possess the allele M.
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