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Astacus Astacus
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9 years ago
Why GP120 and GP41 proteins are not detectible by immune system?

These two are viral (HIV) proteins attached to host mebrane. Why immune system dosent react to them?
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wrote...
9 years ago
Why GP120 and GP41 proteins are not detectible by immune system?

They are detectable. Where did you get that idea from?
Astacus Author
wrote...
9 years ago
Well, then why our innune system dosent and get rid of HIV with antibodies?
wrote...
Valued Member
Educator
9 years ago
Watch this, explains it well...

Astacus Author
wrote...
9 years ago
I know the HIV cycle and video dosent aswer my question... If GP120 and GP41 are viral proteins they should be detected by immune system and in some time there should be alot of antibodies against them in host blood. Next step should be opsonisation and getting rid of virus.
wrote...
Valued Member
Educator
9 years ago
To check if someone is infected with the virus, I believe artificial GP120 and GP41 antigens are used. If these antigens react with antibodies found in the blood of an infected person, coagulation takes place, and this means the person has been previously infected with the virus. This suggests that the immune system detects HIV, but the mechanism of action of HIV, binding to CD4 T cells, then integrating its genome into the host, cannot be controlled.
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