Lymphatics & Immunity

I could use some help on these questions. Any help would be appreciated.

1) The antigen combining sites of antibodies are located in the _____, while the complement-binding site is in the _____.

A) heavy & light variable chains, light constant chains
B) heavy & light variable chains, heavy constant chains
C) constant regions of both heavy & light chains, light variable chains
D) variable regions of both heavy & light chains, heavy variable chains


2) "T" Lymphocytes respond to a present foreign protein by _____ during _____ immunity.

A) performing costimulation,  cell-mediated
B) producing perforin, cell-mediated
C) producing antibodies, humoral
D) Choice A & B
E) Choice B & C

3) To successfully perform antibody-mediated immunity, which cell type is directly involved in making a secretion to destroy the antigen covered material?

A) T-cytotoxic
B) B-cell
C) Plasma cell
D) antigen-presenting cell
E) all of the above except choice C