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BioMajor2017 BioMajor2017
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Posts: 9
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9 years ago
cystic fibrosis occurs because of a mutation in the gene that codes for an active transport(CFTR) in lung tissue that is responsible for transporting chloride ions from the interior lung surface into the cell. In the mutated protein, chloride ions are not transported across cell membranes, and build up in the extracellular fluid. About 1 in 2000 humans inherit a mutation in the CFTR transporter and show symptoms of the disease
The CFTR transporter is a 
a.   Cl- glucose antiporter
b.   Voltage gated anion pump
c.   ATP activated Cl- pump
d.   Cl- uniporter
e.   E. Neurotransmitter gated Cl- channel

The cell death cascade becomes irreversible once
a.   intiator procaspases become activated
b.   executioner procaspases become activated
c.   cells form blebs
d.   the FAS ligand binds to G protein coupled receptors
e.   when IAP proteins bind activated caspases
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