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Morbesety Morbesety
wrote...
13 years ago
what is the difference between allosteric inhibitor & feedback inhibition?...
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wrote...
Educator
13 years ago
Morbesesty, the two terms are totally unrelated!

Allosteric enzymes are usually found at metabolic control points. Frequently, these are the first steps in pathways. Regulation of the entire sequence of enzymatic steps is most efficiently accomplished by turning on or turning off the pathway at the first step. When the control is exerted by the end product of the pathway, the inhibition (or activation) is termed "feedback regulation". An example to be considered later is the feedback inhibition by ATP of the glycolytic pathway. Allosteric regulation always involves the binding of a metabolite to a site separate from the enzyme active site.
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