× Didn't find what you were looking for? Ask a question
Top Posters
Since Sunday
a
5
k
5
c
5
B
5
l
5
C
4
s
4
a
4
t
4
i
4
r
4
r
4
New Topic  
love1995 love1995
wrote...
Posts: 20
Rep: 0 0
8 years ago
Describe cellular and humoral immune responses.

     How are they different from each other?                                        Give examples of diseases that compromise each of these responses. Your examples must include how each disease compromises the response.
Read 2569 times
2 Replies

Related Topics

Replies
wrote...
8 years ago
one of the differnces is one is b-cell mediated and the other is t cell mediated.
wrote...
Educator
8 years ago
Describe cellular and humoral immune responses.

The immune system differentiates dual groups of the foreign substances. Individual group contains of antigens which are easily circulating in body. These contain viruses, molecules, and foreign cells. The second group contains of self-cells which show to aberrant MHC proteins. The Aberrant MHC proteins could initiate from antigens which have been immersed and cracked down (exogenous antigens) or starts virus‐infected besides tumor cells which are aggressively synthesizing the foreign proteins or endogenous antigens. Dependent on the kind of the foreign invasion, two dissimilar immune replies take place:

Humoral response

The antibody‐mediated response or humoral response includes B cells which identify antigens or the pathogens which are circulating in lymph or in the blood on the other hand “humor” is a medieval term for body fluid. The response keep an eye on this chain of events:

1.   The Antigens bind to the B cells.
2.   The Interleukins or the helper T cells costimulate to B cells. In maximum cases, composed with an antigen and a costimulator that are essential to activate the B cell and initiate the B cell proliferation.
3.   The B cells proliferate in addition the produce plasma cells. However, the plasma cells tolerate antibodies through the indistinguishable antigen specificity as antigen receptors of initiated B cells. These antibodies are totally released and also circulate through the body, required to antigens.
4.   The B cells produce to memory cells. However, memory cells deliver the future immunity.

Cellular

The cellular reply involves regularly T cells and replies to somewhat cell that shows aberrant MHC markers, tumor cells, together with cells invaded by pathogens, or the transplanted cells. The subsequent chain of events defines this immune response:
1.   A Self-cells or the APCs presenting foreign antigens bind to T cells.
2.   Interleukins which are secreted by APCs or collaborator T cells costimulate beginning of the T cells.
3.   If MHC‐I and the endogenous antigens are showed on plasma membrane, The T cells proliferate, creating cytotoxic T cells. However, the Cytotoxic T cells end cells showing the antigens.
4.   If the MHC‐II and an exogenous antigens are showed on T cells proliferate, plasma membrane, producing helper T cells. The helper T cells release to interleukins in addition other cytokines, which always stimulate B cells to produce the antibodies which bind to antigens and the stimulate nonspecific agents that are used to destroy the antigens.
Differences
1.   The Cellular immune responses usually refer to those which take place inside a cell. However, humoral responses always take place in the blood or in other extracellular fluids.
2.   The cellular responses contain self-destruction in event of the overwhelming infection and provide signaling to supplementary cells in which an infectious agent is present. The Humoral responses are the responses that focused on production of the antibodies and proteins that are custom-built to exact infectious agents which is bonding in addition neutralizing them.
3.   Cancer can give and take the cellular response through inhibiting apoptosis that always resulting in cells which live far extended than they should. However, this is somewhat that is contradictory to popular conception of the cancer as actuality a matter of the runaway mitosis.

References

Humoral Immune Response. (n.d.). Retrieved from http://www.bio.davidson.edu/people/sosarafova/Assets/Bio307/liwoeste/Humoral%20Immune%20Response.html
The immune system and vaccination. (n.d.). Retrieved from http://www.immune.org.nz/immune-system-and-vaccination
New Topic      
Explore
Post your homework questions and get free online help from our incredible volunteers
  1059 People Browsing
Related Images
  
 1302
  
 189
  
 280
Your Opinion
Do you believe in global warming?
Votes: 370