Genetics Which of the following mutations could explain the loss of regulation i

Milk products such as cheeses and yogurts are dependent on the conversion by various anaerobic bacteria, including several Lactobacillus species, of lactose to glucose and galactose, ultimately producing lactic acid. These conversions are dependent on both permease and beta-galactosidase as part of the lac operon. After selection for rapid fermentation for the production of yogurt, one Lactobacillus subspecies lost its ability to regulate lac operon expression (Lapierre, L., et al. 2002. J. Bacteriol. 184: 928–935).

Would you consider it likely that in this subspecies the lac operon is “on” or “off”?
The correct answer is "on"
Part B
Which of the following mutations could explain the loss of regulation in this subspecies?
Select all that apply.
Select all that apply.
    lac Z -
    lac O c
    lac I s
    lac I -

^you can pick as many that are right for part B