You need to login first

Login information

Haven't yet registered?

×
* * * *

Support Us

If you found our community helpful, your small donation will continue to help us reach more students around the globe. You may also like us on Facebook or follow us on Twitter.
Pages: 1     Go Down
  New Topic  |  Print  
What is the substrate of pepsin?
Read 1258 times | 1 Replies | Average Rating: Not Rated Yet
buddhadog
Jellyfish
*
Posts: 23
Points: 47
Rep:  +0   -0


For a more comfortable homework help experience, try HomeworkClinic.com.
and what does pepsin do to its substrate?

Report this PostReport Abuse
replies
Reply# 1
Posts: 29
Points: 15
Rep:  +0   -0

A year ago

The substrate is proteins, and the products are peptides.

Pepsin is a protease, i.e. an enzyme that catalyzes the breakdown of proteins. In humans, it is secreted by certain cells (called chief cells) in the lining of the stomach.

Specifically, pepsin breaks the peptide bonds linking amino acids in the chains found in proteins. Pepsin cannot break all peptide bonds, however. It is particularly efficient at hydrolyzing the bonds on the C-terminal side of tyrosine, phenylalanine, and tryptophan. It does not attack bonds involving glycine, alanine, or valine residues.

So you can think of pepsin as being like someone taking a pair of scissors to a long piece of string, and cutting in certain places. The result of peptic activity is shorter chains, called peptides.

These peptides are later further digested by other enzymes secreted by the pancreas and small intestine. The final result is free amino acids, which can be absorbed by the villi of the small intestine.



Report this PostReport Abuse
Pages: 1     Go Up New Topic Print
 
Related Topics
Replies Author Last post
2
Replies
Biochemistry | Started by ilikepie1234 | Views: 1739
Last post Last post by Suresh
A year ago
3
Replies
Biochemistry | Started by smlan3 | Views: 254
Last post Last post by smj545
A year ago
1
Reply
Upper-Year Courses | Started by Illuminatus | Views: 409
Last post Last post by leroy3
A year ago
1
Reply
Cell Biology | Started by smokinjoe531 | Views: 926
Last post Last post by leon1977
A year ago
Note: This topic is currently locked from adding new posts. Only administrators and moderators can reply. If you'd like to contribute to this topic, start a new thread and make reference to this one. Otherwise, contact a moderator for more options.