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Home Q & A Board Biology-Related Homework Help Anatomy and Physiology
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ehd123 ehd123
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8 years ago
What is the ionic mechanism that can interrupt the depolarization of a neuron?
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12 Replies
B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience

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wrote...
#1
Educator
8 years ago
What causes depolarization?

Sodium ions diffuse across the membrane. So, the inside becomes more positive than the outside.

The question I guess is what would prevent this?
ehd123 Author
wrote...
#2
Valued Member
8 years ago
Exactly the questions are not very clear.. I for example think that the closure of voltage gated Na channels and the opening of the Voltage gated K channels might be what they question is asking for here.. but these are the initial steps for repolarization.. Not sure =/
B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience
wrote...
#3
Educator
8 years ago
Ehd123, remind me, what causes repolarization? Is it the influx of potassium ions?
ehd123 Author
wrote...
#4
Valued Member
8 years ago
Depolarization: Na in,
Repolarization: K out
Hyperpolarization: K channels stay open leading to K ions leaving the cell and negative resting mb potential
B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience
wrote...
#5
Educator
8 years ago
After repolarization, how do potassium ions get replenished and when to sodium ions leave the cell to restart the process?
ehd123 Author
wrote...
#6
Valued Member
8 years ago
This all then happens at the refractory period through the Na/K/ATPase pump
B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience
wrote...
#7
Educator
8 years ago Edited: 8 years ago, bio_man
Still a bit confused, but I'll run with the idea, thanks
ehd123 Author
wrote...
#8
Valued Member
8 years ago
Same here.. I found this document.. it helps a bit.. But to be honest, I am a neuro major, and action potentials are the most confusing thing to understand even though we've been through this material 2 years ago. I will soon go over that material although it gets freakishly detailed with "funny" Na channels and slow K channels etc.. Will try to clarify the whole process again soon
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B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience
wrote...
#9
Educator
8 years ago
Try this animation, I just uploaded it:

[Animation] - The Nerve Impulse
ehd123 Author
wrote...
#10
Valued Member
8 years ago
Yaay! So what I said was right!  Smiling Face with Glasses
and what interrupts the depolarization is indeed the closure of Na V-gated channels and opening of the K Vgated channels!
B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience
wrote...
#11
Educator
8 years ago
Case closed! I'll mark the topic solved - feel free to reverse it
ehd123 Author
wrote...
#12
Valued Member
8 years ago
Alrighty! Thanks Slight Smile
B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience
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