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GoodKnight GoodKnight
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8 years ago
I guess my question is two fold.

A. are there Viruses without a capsid?

B. What is uncoating? Is it in relation to the genome of the virus? as in only when the genome of the virus is exposed it is considered uncoating? Because I know some viruses enter the cytoplasm and then enter the nucleus. So the uncoating is in the nucleus? Or the cytoplasm?
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Educator
8 years ago
A. are there Viruses without a capsid?

Yes, and here's a reference: http://onlinelibrary.wiley.com/doi/10.1002/9780470015902.a0023269/abstract;jsessionid=072D38E869DCD8D8B4C78137AF85E625.f01t03?systemMessage=Wiley+Online+Library+will+be+unavailable+on+Saturday+27th+February+from+09%3A00-14%3A00+GMT+%2F+04%3A00-09%3A00+EST+%2F+17%3A00-22%3A00+SGT+for+essential+maintenance.++Apologies+for+the+inconvenience.

With some viruses, the genome is completely released from the capsid during or after penetration. The penetration may occur in the plasma membrane, when it fuses with it, or it may occur in the nucleus
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