Streptococcus mutans is facultatively anaerobic, gram-positive coccus commonly found in the human oral cavity and is a significant contributor to tooth decay. Streptococcus mutans possesses three virulence factors: water insoluble glycans, acid tolerance, and production of lactic acid.

The growth and metabolism changes local environmental conditions (e.g., pH, coaggregation, and substrate availability), thereby enabling more fastidious organisms to further colonize after them, forming dental plaque.

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