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oemBiology oemBiology
wrote...
Posts: 1245
7 years ago
Referring to following articles, I would like to know on any protection mechanism within our body to control the overstimulate neurons along the nervous system.

Does anyone have any suggestions?
Thanks in advance for any suggestions


http://bigpictureeducation.com/venoms-and-nervous-system
What do neurotoxins do?

Neurotransmitters, chemicals such as acetylcholine, transmit information across the gap (synapse) between neurons (nerve cells). Chemicals that are similar in structure to neurotransmitters can also stimulate the postsynaptic receptors of an adjacent neuron. This binding action can be agonistic (stimulatory), in which case the impulse is still sent: venoms that act in this way can overstimulate neurons, causing muscle spasms (tetany) and an increased heart rate.

Some toxins have an antagonistic (inhibitory) effect. In this case, the nerve impulse is blocked and symptoms include muscle paralysis and a low heart rate (bradycardia).

Some neurotoxins inhibit the enzyme that breaks down the neurotransmitter–receptor complex, which also causes overstimulation of that neural pathway. This is seen in some types of rattlesnake or mamba venom.
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wrote...
Educator
7 years ago

The effect of neurotoxins is based on the substance itself. Each one works differently, where some suppress the breakdown of naturally occurring neurotransmitters, others prevent their release.

Common examples of neurotoxins include lead, ethanol (drinking alcohol), Manganese glutamate, nitric oxide (NO), botulinum toxin (e.g. Botox), tetanus toxin, and tetrodotoxin. Like I mention, each one of these has a different mechanism of action that you'd have to research individually to find out

Let me know if that helps
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