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Anonymous Annonn
wrote...
A year ago
Bar eye in Drosophila is X-linked and exhibits incomplete dominance.  Wild-type females have an average of 810 facets in the eye, while homozygous Bar females have an average of 59 facets.  Heterozygous females have a kidney-shaped eye with an average of 447 facets.  Males have either wild-type-shaped eyes with about 810 facets or Bar eyes with about 60 facets.


A) An autosomal recessive allele purple results in purple eyes when homozygous.  A female with Bar but homozygous for red eyes is mated with a male with normal-shaped but purple eyes.  What are the expected phenotypic ratios in the F1 generation?

a*F1 females and males will have kidney-shaped eye, red eyes.

b*F1 females will have bar eye, red eyes, and males will have kidney-shaped eye, red eyes.

c*F1 females and males will have bar eye, red eyes

d*F1 females will have kidney-shaped (447 facet) red eyes, and males will have Bar eye (60 facet) red eyes.


B) An autosomal recessive allele purple results in purple eyes when homozygous.  A female with Bar but homozygous for red eyes is mated with a male with normal-shaped but purple eyes giving a F1 generation. If one of the F1 males is mated with an F1 female, what are the expected phenotypes in the F2 generation for females?

a*1/16 red-eyed females with Bar eyes; 3/16 purple-eyed female Bar eyes; 1/16 red-eyed females with kidney-shaped eyes; and 3/16 purple-eyed female with kidney-shaped eyes

b*1/4 red-eyed females with Bar eyes; and 1/4 purple-eyed female with kidney-shaped eyes

c*3/16 red-eyed females with Bar eyes; 1/16 purple-eyed female Bar eyes; 3/16 red-eyed females with kidney-shaped eyes; and 1/16 purple-eyed female with kidney-shaped eyes

d*1/8 red-eyed females with Bar eyes; 1/8 purple-eyed female Bar eyes; 1/8 red-eyed females with kidney-shaped eyes; and 1/16 purple-eyed female with kidney-shaped eyes


C) An autosomal recessive allele purple results in purple eyes when homozygous.  A female with Bar but homozygous for red eyes is mated with a male with normal-shaped but purple eyes giving a F1 generation. If one of the F1 males is mated with an F1 female, what are the expected results in the F2 generation for males?

a*3/16 red-eyed males with Bar eyes; 1/16 purple-eyed male Bar eyes; 3/16 red-eyed males with kidney-shaped eyes; and 1/16 purple-eyed male with kidney-shaped eyes

b*3/16 red-eyed males with Bar eyes; 1/16 purple-eyed male with Bar eyes; 3/16 wild-eyed males with red eyes; and 1/16 purple-eyed males with wild-shaped eyes

c*1/16 red-eyed males with Bar eyes; 3/16 purple-eyed male Bar eyes; 1/16 red-eyed males with kidney-shaped eyes; and 3/16 purple-eyed male with kidney-shaped eyes

d*1/16 red-eyed males with Bar eyes; 3/16 purple-eyed male with Bar eyes; 1/16 wild-eyed males with red eyes; and 3/16 purple-eyed males with wild-shaped eyes
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wrote...
Staff Member
A year ago
Males have one X chromosome and one Y chromosome. Females have two X chromosomes. Males inherit the X chromosome from the mother and the Y chromosome from the father. Females inherit one copy of the X chromosome from each parent. The bar eye is X-linked and alleles are incompletely dominant.

Let XB be the wildtype allele on the X chromosome for wildtype-shaped eyes
Let Xb be the mutant allele on the X chromosome for bar-shaped eyes

In incomplete dominance, the heterozygotes (XBXb) exhibit kidney-shaped eyes which is a blend of two phenotypes. 

The purple eye is an autosomal recessive trait. In autosomal recessive inheritance, the presence of two copies of recessive alleles is required to exhibit the trait.

Dominant P allele = red eyes
Recessive p allele = purple eyes

In X-linked inheritance, there is no male-to-male transmission of trait

Genotype of parents:

Genotype of bar-shaped, red-eyed female parent: XbXb PP
Genotype of normal-shaped, purple-eyed male parent: XBY pp

Parent cross: XbXb PP * XBY pp

GametesXbPXbP
XBpXBXb PpXBXb Pp
YpXbY PpXbY Pp

F1 offspring phenotypic ratio: 


F1 males: 100% bar eye (60 facets), red eyes (XbY Pp) 
F1 females: 100% kidney-shaped (447 facets), red eyes (XBXb Pp)

Thus, all F1 offspring will have red eyes. F1 females will have kidney shaped eyes. F1 males will have bar shaped eyes.

F1 * F1: XBXb Pp * XbY Pp

See attachment!

Therefore, all individuals with kidney-shaped eyes are females. Males do not have kidney shaped eyes because they have only one X chromosome.

All F1 offspring have red eyes. All F1 females have kidney-shaped eyes and all F1 males have bar-shaped eyes.

F2 phenotypic ratio:

kidney-shaped, red-eyed female = 3/16
kidney-shaped, purple-eyed female = 1/16
bar-shaped, red-eyed female = 3/16
bar-shaped, purple-eyed female = 1/16
wildtype-shaped, red-eyed male = 3/16
wildtype-shaped, purple-eyed male = 1/16
bar-shaped, red-eyed male = 3/16
bar-shaped, purple-eyed male = 1/16

A) The correct option is d. F1 females will have kidney-shaped (447 facets) red eyes, and males will have Bar eye (60 facets) red eyes

B) The correct option is c. 3/16 red-eyed females with Bar eyes; 1/16 purple-eyed females with Bar eyes; 3/16 red-eyed females with kidney-shaped eyes; 1/16 purple-eyed females with kidney-shaped eyes.

C) The correct option is b. 3/16 red-eyed males with Bar eyes; 1/16 purple-eyed males with Bar eyes; 3/16 wild-eyed males with red eyes; 1/16 purple-eyed males with wild-shaped eyes
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