× Didn't find what you were looking for? Ask a question
Top Posters
Since Sunday
5
o
5
4
m
4
b
4
x
4
a
4
l
4
t
4
S
4
m
3
s
3
New Topic  
akbyst akbyst
wrote...
13 years ago
A 50- year old worker at a school cafeteria went to her primary care physician complaining of tiredness, shaking chills, a pain in her loin, and a burning sensation on passing urine, which she was doing more frequently than normal. On examination, her doctor noted that she seemed a bit pale and that she had some suprapubic tenderness. Her urine had a positive result for nitrite, pus cells, blood, and protein.   The doctor took a blood and urine sample for confirmation and sent them to the  hospital laboratory. A diagnosis of pyelonephritis was made and she was started on antibiotics. The following day the laboratory results were available. The full blood count showed a neutrophilia and a pure culture of Escherichia coli was grown from the urine.

1.   What is the most likely specific serotype of the causative agent? .

2.   What is the disease pathogenesis? (narrative format)

A 53-year old lady returned from a visit to Lahore, India complaining of feeling generally unwell. She had a temperature and a cough. She attended a clinic where she was seen by a doctor who confirmed that she had a temperature of 38° C and he noticed a rash on the upper chest. She was admitted to hospital for investigation, which included a thick and thin film for malaria, a full blood count, urea and electrolytes, a chest X-ray, and blood cultures. The malaria investigation was negative, the chest X-ray showed patchy basal consolidation, the full count revealed a relative lymphocytosis, and gram-negative bacilli were seen in the blood culture. A provisional diagnosis of enteric fever was made and she was started on appropriate antibiotics. The diagnosis was confirmed by isolation of Salmonella typhi from the blood cultures.

1.   What is the causative agent?

2.   How does it enter the body ?


A 53-year old lady returned from a visit to Lahore, India complaining of feeling generally unwell. She had a temperature and a cough. She attended a clinic where she was seen by a doctor who confirmed that she had a temperature of 38° C and he noticed a rash on the upper chest. She was admitted to hospital for investigation, which included a thick and thin film for malaria, a full blood count, urea and electrolytes, a chest X-ray, and blood cultures. The malaria investigation was negative, the chest X-ray showed patchy basal consolidation, the full count revealed a relative lymphocytosis, and gram-negative bacilli were seen in the blood culture. A provisional diagnosis of enteric fever was made and she was started on appropriate antibiotics. The diagnosis was confirmed by isolation of Salmonella typhi from the blood cultures.

1.   What is the causative agent?

2.   How does it enter the body ?

   A 19-year old college student was in his usual state of health until the evening before admission, when he went to bed with a headache. He told his room-mate that he felt feverish, and on the following morning his roommate found him in bed, moaning and lethargic. He was taken to the emergency room, where he appeared toxic and drowsy but oriented. His temperature was 40° C, his heart rate was 126/min, and his blood pressure was 100/60 mmHg. His neck was supple. He had an impressive, nonblanching purpuric rash, most prominent on the trunk, wrists, and legs. His white blood cell count was 26,000 micro liters-1 with 25% band forms. The platelet count was 80,000 micro liters -1. Blood cultures were obtained and the patient was started on intravenous ceftriaxone. Blood cultures revealed gram-negative diplococci which grew best on Chocolate Agar, and were oxidase positive. The cerebrospinal fluid (CSF) glucose was low,  protein was elevated, and increased number of white blood cells, mainly polys.

1.   What is the causative agent?

2.   How does it enter the body?
Read 2837 times
1 Reply

Related Topics

Replies
wrote...
Valued Member
Educator
13 years ago
First one: Uropathogenic E. coli

Second one: Salmonella typhimurium or Salmonella enterica typhi... Comes from food infected with the species.

Third one: Neisseria meningitidis... See: http://www.ppdictionary.com/bacteria/gnbac/meningitidis.htm
New Topic      
Explore
Post your homework questions and get free online help from our incredible volunteers
  881 People Browsing
 108 Signed Up Today
Related Images
  
 503
  
 3266
  
 403
Your Opinion
Which of the following is the best resource to supplement your studies:
Votes: 249