× Didn't find what you were looking for? Ask a question
Top Posters
Since Sunday
a
5
k
5
c
5
B
5
l
5
C
4
s
4
a
4
t
4
i
4
r
4
r
4
Home Q & A Board Biology-Related Homework Help Genetics and Developmental Biology
New Topic  
morgan795 morgan795
wrote...
Posts: 16
Rep: 2 0
8 years ago
Sickle-cell disease is caused by a mutation that changes a single codon of the b-globin gene from 5’-GAG (encoding glutamic acid) to 5’-GTG (encoding valine).  Heterozygotes have a distinct phenotype involving malaria resistance.  Which of the following terms apply to this mutation?
Select all that applies
A) synonymous (or silent) mutation
B) missense mutation
C) nonsense mutation
D) frameshift mutation
E) null (or loss-of-function) mutation
F) transversion
G) indel mutation
H) neomorphic (or gain-of-function) mutation
I) transition
Read 561 times
3 Replies

Related Topics

Replies
wrote...
#1
Educator
8 years ago
In genetics, a missense mutation (a type of nonsynonymous substitution) is a point mutation in which a single nucleotide change results in a codon that codes for a different amino acid.

So, B

Quote from: morgan795 (8 years ago)
E) null (or loss-of-function) mutation

Would also say this Upwards Arrow
wrote...
#2
8 years ago
Quote from: bio_man (8 years ago)
In genetics, a missense mutation (a type of nonsynonymous substitution) is a point mutation in which a single nucleotide change results in a codon that codes for a different amino acid.

So, B

Quote from: morgan795 (8 years ago)
E) null (or loss-of-function) mutation

Why would not be frameshit too?
Would also say this Upwards Arrow
wrote...
#3
Educator
8 years ago
Upwards Arrow ?
New Topic      
Quick Reply
Explore
Post your homework questions and get free online help from our incredible volunteers
  1147 People Browsing
 105 Signed Up Today
Start New Topic Take the Tour CoursesNew Study Tools Topics Trending Browse by Textbook
Live Chat
Related Images
  
 298
  
 295
  
 287
Your Opinion
What's your favorite math subject?
Votes: 293
Previous poll results: Do you trust social media networks with protecting your privacy?