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SlideshowReport

Cycles of Sleep and Melatonin Secretion

Description
Normally, melatonin secretion begins in the evening, approximately six hours before the midpoint of sleep. Most people with seasonal affective disorder begin secreting melatonin earlier, showing a phase delay between cycles of melatonin and sleep. A few people with this disorder show a phase advance, with melatonin secretion beginning at a later time. (Based on data from Lewy et al., 2006.)
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