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SlideshowReport

Mechanisms of differentiation

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(a) Positional information (b) Induction (c) Inhibition I I I l r I r r I I 1 I I l I I l I l r I I r I I l I I 1 ' ‘ l ' ‘ E All cells have the potential to differentiate as . redawhite, or blue. The differentiation of each One cell (green) produces a molecule One cell (red) produces an inhibitor that C9” '5 determined by the concentration Of a that causes neighboring cells to differ— prevents neighboring cells from I morphogen along a gradient. entiate with a particular fate (blue). differentiating with a particular fate. r If IT l I l Blue 3 E i S 5 cells I I '5 8" l r fie i 5 a 1 a e ‘ O H- U 0 Example: Moving the organizer cells from Example: Drosophi/a cells expressing one frog embryo to another induces the achaete (brown) become ectoderm and development of a second body axis. inhibit neighboring cells from doing the same.
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