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SlideshowReport

Insulator and enhancer interactions

Description
(a) (b) Enhancer Promoter Insulator Transcription of gene A Gene A ON Enhancer Promoter (C) Insulator Enhancer activity helps initiate transcription, ,,,,,,,,,,,,,,,,,,,,,,,,,,,,, \ Insulator sequence 1 blocks enhancer Gene A action and can... OFF GeneB Enhancer Promoter ON Promoter (d) Insulator /-l Gene A OFF Enhancer Promoter Gene A ON (e) Gene 8 OFF TATA TATA promoter1 promoter 2 ON Gene A Insulator . . .redirect enhancer activity 1 A particular enhancer activates a gene in preference over a nearby enhancer whose ,aqifii‘fllibifikfl; Insulators may direct the « formation of DNA ‘1 loops that contain f enhancers and ‘ the genes they activate. to another gene. ‘ i
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