Summary of T-Cell Types

Summary of T—Cell Types Cells Function Markers Effector Molecules Th1 helper T cells Modulate and coordinate an immune response CD4 INF-y, TNF-B, Steer toward a cell-mediated response  helper T cells Modulate and coordinate an immune response CD4 lL-4, IL-5, lL-6, |L-10, TGF-B Steer toward an antibody-mediated response Cytotoxic T cells Kill target cells that have been infected by an endogenous CDB, various degradative enzymes. antigen such as a virus INF-y, INF, Regulatory T cells Act as downregulators of the immune response Usually CD4, IL-10, TGF-B CD25 Play an important role in immunological tolerance