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Graph showing oral administration of a single-dose drug. The time of onset is 2 hours and the end of ...

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Graph showing oral administration of a single-dose drug. The time of onset is 2 hours and the end of drug action is 8 hours. This means that the drug has a duration of action of 6 hours. The plasma t 1⁄2 is about 4 hours (time it takes to decrease its concentration by one-half, or 50 percent).
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