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SlideshowReport

Structure of cytochrome c oxidase (complex IV)

Description

Four electrons are donated, one at a time, by reduced cyt c, to the CuA center, through heme a, and on to the catalytic site (binuclear a3–CuB site) where one molecule of O2 is reduced, yielding two molecules of H2O.

Protons are pumped from the matrix side to the intermembrane space (IMS) side of the membrane.
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