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SlideshowReport

Structure of phospholipase A2

Description
An enzyme that metabolizes membrane phospholipids.

Catabolism of phospholipids at membrane–water interfaces is important both in modification of membrane structure and as a source of second messengers and other regulators.

The crystal structure of the porcine pancreas phospholipase A2 reveals the catalytic triad (D99-H48-water) and the active site Ca2+ ion, liganded to a second water molecule (W2).
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