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SlideshowReport

Methyl group metabolism and homocystinuria

Description
Serine hydroxymethyltransferase catalyzes the entry of one-carbon units into the tetrahydrofolate (THF) pool.

A deficiency of methylenetetrahydrofolate reductase (MTHFR) or methionine synthase blocks the conversion of homocysteine to methionine.
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