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SlideshowReport

Glutathione reaction with compound (denoted RX)

Description
Glutathione reacts with such a compound (denoted RX) as shown here, followed by cleavage of the g-glutamyl and glycyl residues and then acetylation by acetyl-CoA to give a mercapturic acid.

This more soluble, less toxic derivative of the original compound can then be excreted in the urine.
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