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SlideshowReport

The insulin receptor and its structural relationship to other transmembrane receptors with protein

Description
Representative proteins in each subfamily are shown.

Some subfamilies have a “kinase insert domain” within the protein kinase module.

VEGF and Eph are regulators of cell movements during development.

The insulin receptor and several related growth factor receptors contain one transmembrane domain per polypeptide chain and have an intrinsic protein tyrosine kinase activity.
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