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SlideshowReport

The conserved DNA-binding domain in steroid receptors

Description
In the center are structural domains within steroid receptors, illustrated for the estrogen receptor.

Above is the DNA-binding domain of the estrogen receptor, showing conserved cysteine residues that contact the bound zinc ions (a zinc finger DNA-binding motif.

At the bottom are the DNA-binding domain sequences of related human receptors, with the conserved cysteine residues highlighted.
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