Top Posters
Since Sunday
a
5
k
5
c
5
B
5
l
5
C
4
s
4
a
4
t
4
i
4
r
4
r
4
SlideshowReport

Backtracking in an elongation complex

Description
Above, the 3’ terminus of the transcript is in the active site (denoted by Mg2+).

Below, the enzyme has slipped backward, leaving the transcript terminus at the end of a nonbase-paired RNA tail, some five nucleotides long.

Transcription can resume either by forward sliding of polymerase back to the structure depicted above or, more likely, by cleavage of the non-base-paired part of the transcript, creating a new base-paired 3’ terminus.
Related Images
Add Comment
Explore
Post your homework questions and get free online help from our incredible volunteers
  940 People Browsing
Your Opinion
Do you believe in global warming?
Votes: 370