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SlideshowReport

The Neuromuscular Junction

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Description
The events at the NMJ produce a muscle action potential
Voltage-gated calcium channels open resulting in an influx of calcium. This causes exocytosis of neurotransmitter (NT) into the synaptic cleft. NT binds to ligand-gated Na+ channels on the motor endplate which cause an influx of Na+ into the muscle. This depolarizes it and results in Ca2+ release from the SR
NT gets broken down
Without this series of events, muscle contraction would not be possible
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