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SlideshowReport

A reciprocal translocation involving the long arms of chromosomes

Description
A reciprocal translocation involving the long arms of chromosomes 9 and 22 results in the formation of a characteristic chromosome, the Philadelphia chromosome, which is associated with chronic myelogenous leukemia (CML).

Normal
chromosome 9
Normal
chromosome 22
q11.2
(BCR)
q34.1 (C-ABL)
Translocation
t(9;22)
+ <ch
(ABL)
Philadelphia
chromosome
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