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Epigenetic changes to DNA, such as methylation, change patterns of gene expression by activating or

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Epigenetic changes to DNA, such as methylation, change patterns of gene expression by activating or repressing transcription. Reversible modification of histones can also alter the pattern of gene expression.


Chromatin Chromosome DNA methylation Methyl group can tag I , DNA and activate or ’repress genes. - Gene Histone tails ‘ Histones are proteins around which DNA can wind for compaction and gene regulation Histone DNA inaccessible, gene inactive o Cengags Lsam'ng. All Rights Reserved. Epigenetic factors (methyl groups, acetyl groups, phosphate groups) Histone modification The binding of epigenetic factors to histone "tails" alters the extent to which DNA is wrapped around histones and the accessibility of genes in the DNA. DNA accessible, gene active
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