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Title: Compare and contrast cell signalling via receptor serine/threonine kinases and R Post by: colleen on Dec 18, 2011 Compare and contrast cell signalling via receptor serine/threonine kinases and Ras.
Title: Re: Compare and contrast cell signalling via receptor serine/threonine kinases and R Post by: how_mendel on Jan 12, 2012 Receptor serine/threonine kinases act through receptor-regulated Smads and the accessory Smad4. Together, they enter the nucleus as a complex following receptor activation.
Ras is regulated by GAPs and Sos (guanine-nucleotide exchange factor). This in turn activates a cascade of phosphorylation events, resulting in the activation of transcription factors that mediate gene expression. |