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Title: What are the assumptions of the zipper model for helix-coil transitions in polypeptides? What is ... Post by: joker on Jan 21, 2018 What are the assumptions of the zipper model for helix-coil transitions in polypeptides? What is meant by cooperativity when describing the helix-coil conformational change?
What will be an ideal response? Title: What are the assumptions of the zipper model for helix-coil transitions in polypeptides? What is ... Post by: analucia_reid on Jan 21, 2018 The assumptions are that (i) each segment in a polypeptide exists in either the c or h configuration, and (ii) that all helical segments are arranged contiguously. Cooperativity when describing the helix-coil conformational change implies that the transition from coil to helix occurs without a significant population of intermediate structural states.
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