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Title: A child who suffers from a persistent viral infection is found to have a deficiency in lymphocyte ... Post by: bwebb03 on Jan 22, 2018 A child who suffers from a persistent viral infection is found to have a deficiency in lymphocyte production and very few T and B cells.
Other bone marrow-derived cells are produced in normal numbers, and MHC molecule expression on cells appears normal. Transfusion of mature T cells from an unrelated donor who had recovered from a previous infection by the same virus would not be expected to help the child clear his infection. Which one of the following is a reasonable explanation for why this therapeutic approach would fail? A. Viral infections are cleared by antibodies, not T cells. B. The patient's own immune system would destroy the transfused T cells before they could respond to the viral infection. C. T cells recognize peptides, not viral particles. D. Donor T cell viral antigen recognition is restricted by MHC molecules not expressed in the patient. E. In responding to the previous infection, the donor would have used up all his T cells specific for that virus. Title: A child who suffers from a persistent viral infection is found to have a deficiency in lymphocyte ... Post by: hetomlinson06 on Jan 22, 2018 Content hidden
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