Biology Forums - Study Force

Occasionally, acute inflammation is initiated by a rapid, massive release of inflammatory chemical mediators, which becomes a life-threatening allergic reaction that can cause cardiovascular shock and death. This condition is known as:
 
  1. chemotaxis.
  2. activation of Hageman factor.
  3. phagocytosis.
  4. anaphylaxis.

Correct Answer: 4
Rationale 1: Chemotaxis is the ability to attract neutrophils and to stimulate them and other cells in the area to become very aggressive. Chemotaxis is not life-threatening.
Rationale 2: The Hageman factor (factor XII) is responsible for activating the kinin system, the clotting cascade, and the plasminogen system. This is a normal response to cellular injury.
Rationale 3: When inflammation occurs, neutrophils are sent to the injury site, where they engulf and digest the foreign materials.
Rationale 4: Anaphylaxis, a life-threatening allergic response that can lead to cardiovascular shock and death, is caused by the rapid, massive release of inflammatory chemical mediators throughout the entire body.
Global Rationale: A number of chemicals, insect stings, foods, and some therapeutic drugs can cause widespread release of histamine from mast cells if the person has hypersensitivity to these substances. This results in a condition known as anaphylaxis which may result in cardiovascular shock and death. Chemotaxis is the ability to attract neutrophils and to stimulate them and other cells in the area to become very aggressive. Chemotaxis is not life-threatening. The Hageman factor (factor XII) is responsible for activating the kinin system, the clotting cascade, and the plasminogen system. This is a normal response to cellular injury. When inflammation occurs, neutrophils are sent to the injury site, where they engulf and digest the foreign materials.