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Title: Which statements about the differences between first- and fourth-generation cephalosporins are ... Post by: 18ryanmandich on Jan 24, 2018 Which statements about the differences between first- and fourth-generation cephalosporins are correct? (Select all that apply.)
a. Fourth-generation agents have more activity against gram-negative organisms. b. First-generation agents are more active against anaerobes. c. First-generation agents have increased resistance to beta-lactamases. d. Fourth-generation agents have an increased ability to reach the cerebrospinal fluid. e. First-generation agents are more vulnerable to destruction by beta-lactamases. Title: Which statements about the differences between first- and fourth-generation cephalosporins are ... Post by: KMyers77 on Jan 24, 2018 ANS: A, D, E
Fourth-generation agents have more activity against gram-negative organisms and have an increased ability to reach the cerebrospinal fluid. First-generation agents are more vulnerable to destruction by beta-lactamases. First-generation agents are not more active against anaerobes, nor do they have increased resistance to beta-lactamases. |