Biology Forums - Study Force

Biology-Related Homework Help Genetics and Developmental Biology Topic started by: sms4lyfe on Feb 12, 2018



Title: How will DNA replication be affected if DNA polymerase I has a mutation that inactivates 5'-to-3' ...
Post by: sms4lyfe on Feb 12, 2018
How will DNA replication be affected if DNA polymerase I has a mutation that inactivates 5'-to-3' exonuclease activity?
 
  What will be an ideal response?


Title: How will DNA replication be affected if DNA polymerase I has a mutation that inactivates 5'-to-3' ...
Post by: Caellis1962 on Feb 12, 2018
The 5'-to-3' exonuclease activity of DNA polymerase I removes the RNA primers from the ends of Okazaki fragments. If this activity is missing, the primers may not be removed from the growing DNA strands.