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Title: Explain the A site, the P site, and the E site in terms of the ribosomal subunit Post by: colleen on Apr 8, 2012 Explain the A site, the P site, and the E site in terms of the ribosomal subunits.
Title: Re: Explain the A site, the P site, and the E site in terms of the ribosomal subunit Post by: chemb on Apr 17, 2012 A theme to this answer should be how a ribosome can interact with and translocate several molecules (e.g., tRNAs) all at once by having structurally distinct subunits (A, P, and E). During translation, an incoming tRNA attaches to the A site of the ribosome in the presence of elongation factor (EF)-Tu. The P site of the ribosome binds the previous tRNA used with the growing polypeptide chain, and the E site serves as an exit/release point for the previously used tRNA.
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