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Biology-Related Homework Help Nursing and Clinical Topic started by: BreakFree on Feb 8, 2015



Title: A client has been diagnosed with a gram-negative bacterial infection and has been prescribed a fluor
Post by: BreakFree on Feb 8, 2015
A client has been diagnosed with a gram-negative bacterial infection and has been prescribed a fluoroquinolone for treatment of this infection. What step of the bacterial DNA replication process is most likely being affected by the use of this medication?
1. It inhibits the enzyme DNA polymerase necessary for DNA replication.
2. It binds to the enzyme topoisomerase IV, preventing the new DNA strands from migrating to opposite sides of the cell, thus preventing bacterial cell replication.
3. It inhibits the relaxation of the supercoil prior to the unwinding process, which terminates replication.
4. It inhibits the unwinding of the two strands of the supercoil, thus terminating replication.


Title: Re: A client has been diagnosed with a gram-negative bacterial infection and has been prescribed a f
Post by: ngin on Feb 11, 2015
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Title: Re: A client has been diagnosed with a gram-negative bacterial infection and has been prescribed a fluor
Post by: BreakFree on Feb 15, 2015
Sounds and feels right, thank you for the rationale.


Title: Re: A client has been diagnosed with a gram-negative bacterial infection and has been prescribed a fluor
Post by: ngin on Feb 16, 2015
I've studied this stuff recently, so I knew what the answer was. Good luck with the rest.