|
Title: all SNPs are RFLPs or not? Post by: prabhjotkaur on Apr 8, 2015 help me regarding this.
Title: Re: all SNPs are RFLPs or not? Post by: bio_man on Apr 8, 2015 I believe a Single Nucleotide Polymorphism (SNPs) is just a complex term for a point mutation - a single base pair change at a specific point in a DNA sequence.
Restriction Fragment Length Polymorphisms (RFLPs) detect differences in segments of pieces of DNA. Differences are due to insertions or deletions, but not SNPs - pieces are generated by cutting with restriction enzymes - sizes of pieces (fragments) are determined by gel electrophoresis. |