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Biology-Related Homework Help General Biology Topic started by: John421 on Apr 20, 2015



Title: Pyruvate (C3H3O3-) becomes acetyl (C2H3O) was it oxidised or reduced?
Post by: John421 on Apr 20, 2015
So when pyruvate (C3H3O3-) becomes acetyl (C2H3O) it has lost 2 oxygens (reduction), but it has also lost an electron (oxidation).

Some sources say pyruvate is oxidised to acetyl-CoA
Other sources say pyruvate is reduced to acetyl-CoA

If both oxidation and reduction happen to a molecule, is there another word you should use other than "oxidation" or "reduction" or does one take presidence over the other or something?


Title: Re: Pyruvate (C3H3O3-) becomes acetyl (C2H3O) was it oxidised or reduced?
Post by: bio_man on Apr 20, 2015
Yes, under aerobic conditions pyruvate is oxidised to acetyl CoA, and then undergoes complete oxidation to carbon dioxide and water. Three-carbon molecule Pyruvate is oxidised by removing hydrogen ions and electrons. NAD is reduced and travels to the electron transport chain.


Title: Re: Pyruvate (C3H3O3-) becomes acetyl (C2H3O) was it oxidised or reduced?
Post by: John421 on May 4, 2015
Is there a reason that it is called oxidation, when both oxidation and reduction seem to take place to pyruvate at the same time?


Title: Re: Pyruvate (C3H3O3-) becomes acetyl (C2H3O) was it oxidised or reduced?
Post by: bio_man on May 4, 2015
when both oxidation and reduction seem to take place to pyruvate at the same time?

When/where does reduction take place?

As mentioned, it is NAD that is reduced and travels to the electron transport chain.