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Biology-Related Homework Help Biochemistry Topic started by: SMK.ANOOP on Sep 4, 2012



Title: would the enzymes pepsin and trypsin function together?
Post by: SMK.ANOOP on Sep 4, 2012
If so, what pH would produce the highest activity

I have a graph that shows trypsin, and it produces the most activity at a pH level of 6, and a graph that shows the activity at a pH level of 1.5.

I need this for my biology lab class, thank you so much.


Title: would the enzymes pepsin and trypsin function together?
Post by: lexitrae on Sep 4, 2012
these two enzymes do NOT function together in the living system ( the body ) as pepsin works at the pH of the stomach ( ~ 2 - 2.5 ) and loses all activity above pH 4.5. Trypsin , a small intestine enzyme , on the other hand, operates at pHs above ~7 ( it is a serine protease ) and loses all activity below pH 5.5 - 6 . So a there is no overlapping pH where one would expect activities of both enzymes.