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Title: How do i calculate allelic frequencies using the Hardy-Weinberg model? Post by: buggingout16 on Sep 1, 2012 Calculate the frequencies of the alleles and the frequencies of the genotypes in a population of 100,000 rabbits, of which 25,000 are white and 75,000 are agouti. White is recessive and agouti is dominant.
Title: How do i calculate allelic frequencies using the Hardy-Weinberg model? Post by: rjcool123 on Sep 1, 2012 Use p + q= 1 and p^2 + 2pq + q^2= 1 with p being the dominant allele and q being the recessive allele. If there are 25,000 white rabbits out of 100,000, 25% or .25 are white so q= .25. p must be .75 since (75,000/100,000= .75 or 1-.25= .75. Now plug these numbers into the second equation to get genotype frequencies. You already know 25% are recessive/recessive. 75% are agouti so this consists of both heterozygotes and homozygous dominants. .75^2= the frequency of homozygous dominant. 2*.75*.25= the frequency of heterozygotes. Hope this helps!
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