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Title: What effect does a calcium channel blocker have on the heart, the blood pressure Post by: ppk on Jul 28, 2011 What effect does a calcium channel blocker have on the heart, the blood pressure, and cardiac output? Why?
Title: Re: What effect does a calcium channel blocker have on the heart, the blood pressure Post by: lewis on Jul 29, 2011 Calcium channel blockers inhibit the opening of calcium channels and ensuing calcium current. Vascular smooth muscle dilates, and heart rate decreases. Vasodilation will result in a decrease in systemic blood pressure, and the decrease in heart rate will decrease cardiac output.
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