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Title: Respiratory Case study Post by: jlhowell on Apr 14, 2013 If the blood volume is 4.7L, what is the H+ deficit? I'm not sure what kind of formula to use!??
Title: Re: Respiratory Case study Post by: bio_man on Apr 14, 2013 Me neither :-\
I found this, however. Could you reply back and tell me if you'd worked with something like this before? Similarly, here's another example: What is the H+ deficit for this patient if you desire the [HCO3-] to be corrected to 35mEq/L? Solution A. H+ deficit can be calculated by the following equation: H+ deficit = 0.5 x Wt x ( [HCO3-]measured – [HCO3-] desired ) Therefore in our clinical example the H+ deficit follows: H+ deficit = 0.5 (70) x (45 – 35) = 0.5 (70) (10) = 350 mEq After having calculated the H+ deficit to correct the severe metabolic alkalosis to a desired [HCO3-] value, you are handed a dilute concentration of HCL. The next question that naturally follows is, HOW MUCH TO GIVE?! Calculating the Volume of 0.1N HCL to infuse Our previous patient who suffering from severe life threatening metabolic alkalosis has an ABG that reveals pH 7.59, [HCO3-] of 45 mEq/L. Having calculated the H+ deficit to correct the [HCO3-] from 45 mEq to 35 mEq, our next concern is to determine the volume of dilute HCL to be infused. The volume of 0.1N HCL to be infused can be calculated by the following equation: Volume of 0.1N HCL = H+ deficit / 100 In our clinical example, the patient has a H+ deficit of 350 mEq. Therefore the volume of 0.1N HCL to be infused to correct the [HCO3-] from 45 mEq/L to 35 mEq/L is: Volume of 0.1N HCL = H+ deficit / 100 = 350 mEq / 100 = 3.5 Liters of 0.1N HCL Rate of Infusion of 0.1N HCL The rate of infusion of HCL should be less than 0.2 mEq/kg/hr! Therefore for our 70kg patient: 70 kg x 0.2mEq/ kg/ hr = 14 mEq/hr. Title: Re: Respiratory Case study Post by: jlhowell on Apr 14, 2013 Bio_man,
I have worked with pH before, but not this specific type of question :s Title: Re: Respiratory Case study Post by: bio_man on Apr 14, 2013 Really unsure, every site I'm visiting, it's telling me to use the formula I provided you in the attachment. Your guess, however, is as good as mine when it comes to using it.
My apologies, hopefully someone else can chime in. |