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Biology-Related Homework Help Biochemistry Topic started by: mikelowry on Aug 4, 2013



Title: What type of receptor is described in the following paragraph?
Post by: mikelowry on Aug 4, 2013
This type of receptor works with the help of a protein that binds the energy-rich GTP molecule. The protein then binds to an enzyme, temporarily altering the enzyme's shape so it can trigger the next step in signaling for the necessary cellular response.




1)


intracellular receptor





2)


ligand-gated ion channel





3)


g protein-coupled receptor





4)


receptor tyrosine kinase


Title: What type of receptor is described in the following paragraph?
Post by: odile98 on Aug 4, 2013
Sounds like a G protein-coupled receptor, to me.

Receptor Tyrosine Kinases tend to use ATP and they don't bind it, they use it to phosphorylize. Ion channels have an entirely different mode of operation than what's described (involving ions, oddly enough). Intracellular receptors are for later in the chain; they would be those triggered in the "next step".

G protein-coupled receptors, however, do exactly what's described. The receptor binds to the G protein, which activates, binding GTP. The activated G protein then activated other signaling proteins to start a signaling cascade.